MSM
| United States Patent | 4,296,104 |
| Herschler | Oct. 20, 1981 |
Therapeutic dimethyl sulfoxide composition and methods of use
Abstract
The use of urea and/or ethanol with pharmaceutical compositions containing DMSO is disclosed. The result is a reduction in the undesirable side-effects normally associated with the application of DMSO compositions, enhancement of the desired physiological effects produced by DMSO compositions, and other benefits. Specific compositions contain DMSO with urea and/or alcohol and may also contain NaCl, KCl and/or acetamide.
The use of DMSO to reduce the mortality rate of fish treated by hyperosmotic delivery is also disclosed.
| Inventors: | Herschler; Robert J. (3080 NW. 8th St., Camas, WA 98607). |
| Appl. No.: | 71,072 |
| Filed: | Aug. 30, 1979 |
| Intl. Cl. : | A61K 31/10, A61K 31/17, A61K 33/14 |
| Current U.S. Cl.: | 424/679; 424/680; 514/588 |
| Field of Search: | 424/322, 153, 337 |
References Cited | [Referenced By]
U.S. Patent Documents
| 3,334,012 | Aug., 1967 | Herschler | 424/337 |
| 3,361,555 | Jan., 1968 | Herschler | 71/103 |
| 3,499,961 | Mar., 1970 | Dobson et al. | 424/68 |
| 3,549,770 | Dec., 1970 | Herschler | 424/337 |
| 3,549,771 | Dec., 1970 | Herschler | 424/337 |
| 3,551,554 | Dec., 1970 | Herschler | 424/7 |
| 3,558,434 | Jan., 1971 | Herschler | 195/81 |
| 3,711,602 | Jan., 1973 | Herschler | 424/45 |
| 3,711,606 | Jan., 1973 | Herschler | 424/45 |
| 3,740,420 | Jan., 1973 | Herschler | 424/45 |
| 3,743,727 | Jul., 1973 | Herschler | 424/181 |
| 4,112,946 | Sept., 1978 | Herschler | 128/253 |
| 4,177,267 | Dec., 1979 | Herschler | 424/238 |
Other References
Primary Examiner: Friedman; Stanley J.
Attorney, Agent or Firm: Blakely, Sokoloff, Taylor & Zafman
8 Claims, No Drawings