NLM database Documents
Record 1 from
database: MEDLINE
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- Title
- Necrotic arachnidism in the northwest United
States and its probable relationship to Tegenaria agrestis (Walckenaer)
spiders.
- Author
- Vest DK
- Address
-
- Source
- Toxicon, 1987, 25:2, 175-84
- Abstract
- Necrotic spider bites in the states of
Washington, Oregon and Idaho, U.S.A., have become increasingly
frequent during the past decade. The great majority of cases
seen by physicians are tentatively diagnosed as 'brown recluse'
spider bite on the basis of clinical manifestations. However,
investigation of over 30 such cases from several northwest
localities has revealed that Tegenaria agrestis, a spider
introduced into the northwest U.S. from Europe, is almost
invariably found at the locality where the bite probably
occurred. Necrotic arachnidism was seen only in areas where
populations of Tegenaria agrestis spiders were well established
and did not occur where Tegenaria agrestis was absent. The
geographical spread of Tegenaria agrestis spiders parallels the
appearance of necrotic arachnidism in several areas. Evaluation
of some individual cases strongly implicates Tegenaria agrestis
as the responsible organism and Tegenaria agrestis is likely
responsible for the majority of 'brown recluse' spider bites
seen in the northwest U.S. Tegenaria agrestis should now be
considered a species of clinical significance capable of
producing marked dermal lesions and, not infrequently, severe
toxicosis in humans. Case histories are presented and
manifestations of poisoning are described.
- Language of Publication
- English
- Unique Identifier
- 87206973
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- MeSH Heading (Major)
- Arachnidism|*ET/PA
- MeSH Heading
- Adult; Animal; Case Report; Human; Male; Middle
Age; Necrosis; Spiders; Support, Non-U.S. Gov't; United States
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0041-0101
- Country of Publication
- ENGLAND
Record 2 from
database: MEDLINE
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- Title
- Loxoscelism and necrotic arachnidism.
- Author
- Wasserman GS; Anderson PC
- Address
-
- Source
- J Toxicol Clin Toxicol, 1983, 21:4-5, 451-72
- Abstract
- The Brown recluse spider has emerged into a
potent venomous creature. Loxoscelism and necrotic arachnidism
is not an infrequent medical problem. Spiders other than L.
reclusa are capable of inflicting painful and persisting
necrotic wounds, however, management of the local cutaneous
lesions are similar. Systemic complications of loxoscelism
appear to be characteristic for spiders of the genus loxosceles.
The authors review an indepth discussion of the spider, venom,
diagnosis, clinical presentation, laboratory findings,
treatment, and prevention. The literature on loxoscelism is
contradictory because of the individuality of the reaction.
Experience with many patients is the only guide to management of
these cases.
- Language of Publication
- English
- Unique Identifier
- 84292409
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- MeSH Heading (Major)
- Arachnidism|DI/*PP/TH; Arthropod Venoms|*PO;
Spider Venoms|*PO; Spiders|*
- MeSH Heading
- Adrenal Cortex Hormones|TU; Animal;
Anti-Inflammatory Agents|TU; Antivenins|TU; Child; Child,
Preschool; Female; Human; Male; Rabbits
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0731-3810
- Country of Publication
- UNITED STATES
Record 3 from
database: MEDLINE
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- Title
- Spider bites [see comments]
- Author
- Blackman JR
- Address
- Rocky Mountain Center for Wilderness and
Environmental Medicine, Boise, ID, USA.
- Source
- J Am Board Fam Pract, 1995 Jul, 8:4, 288-94
- Abstract
- BACKGROUND: This review provides the physician
with a clinical approach to the diagnosis and management of
spider bites. It examines the recent literature concerning
management of bites causing dermonecrosis, secondary infection,
neuromuscular damage, and allergic reactions. METHODS: Using the
key words "spider bites," "brown recluse spider
bites," "necrotic arachnidism," "black widow
spider bites," "latrodectism," and "Tegenaria
agrestis (Hobo spider)," the MEDLINE files were researched
for articles pertinent to the practicing physician. Texts
related to spiders and spider bites were also consulted. RESULTS
AND CONCLUSIONS: At least 60 species of spiders have been
implicated in human bites. Most cause bites of minimal medical
importance, requiring little treatment. Some (brown recluse,
Hobo spider) cause severe cutaneous and systemic reactions
requiring intensive medical management. The black widow bite can
cause severe neurologic problems requiring the use of antivenin.
Spider bites are frequently difficult to diagnose because the
spider is not seen at the time of the suspected bite. Such bites
should be labeled arthropod bites, vector unknown.
- Language of Publication
- English
- Unique Identifier
- 96055407
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- MeSH Heading (Major)
- Arachnidism|*/DI/PC/PP/TH
- MeSH Heading
- Anti-Infective Agents|TU; Dapsone|TU;
Diagnosis, Differential; Folic Acid Antagonists|TU; Human;
Leprostatic Agents|TU; Prognosis
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW LITERATURE
- ISSN
- 0893-8652
- Country of Publication
- UNITED STATES
Record 4 from
database: MEDLINE
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- Title
- Brown recluse spider bites of the upper
extremity.
- Author
- DeLozier JB; Reaves L; King LE Jr; Rees RS
- Address
- Department of Plastic Surgery, Veterans
Administration Medical Center, Nashville, Tenn.
- Source
- South Med J, 1988 Feb, 81:2, 181-4
- Abstract
- Brown recluse spider bites may cause painful,
necrotic, slow-healing wounds. When these bites involve the hand
and upper extremity, they can also create severe functional
deficits and long-term disability. We reviewed an 11-year
experience with brown recluse bites to the hand and upper
extremity. Data from patients (n = 31) indicated a 20% incidence
of functional complications (n = 6) unless conservative wound
management, dapsone, and antibiotics were used. Delayed surgical
excision was preferable until wounds were free from active
inflammation. Painful, recurrent wound breakdown and hand
dysfunction were more common with early surgical excision. These
complications were successfully treated with steroids,
sympathetic blockade, and early aggressive physical therapy.
- Language of Publication
- English
- Unique Identifier
- 88127257
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- MeSH Heading (Major)
- Arachnidism|*/CO/PA/TH; Arm|*/PA
- MeSH Heading
- Adolescence; Adult; Female; Hand|PA; Human;
Male; Middle Age; Support, U.S. Gov't, Non-P.H.S.; Wound Healing
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0038-4348
- Country of Publication
- UNITED STATES
Record 5 from
database: MEDLINE
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- Title
- Presumed arachnidism. A case report (in
Connecticut).
- Author
- Hillis TJ; Grant Kels JM; Jacoby LM
- Address
-
- Source
- Int J Dermatol, 1986 Jan, 25:1, 44-8
- Abstract
- An 8-year-old boy with multiple (up to 12)
hemorrhagic and necrotic blisters was eventually diagnosed as
being the victim of probable spider bites. Arachnidism,
specifically loxoscelism (brown recluse spider bite), is unusual
in the northeastern United States.
- Language of Publication
- English
- Unique Identifier
- 86138814
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- MeSH Heading (Major)
- Arachnidism|CL/EP/*PA/TH
- MeSH Heading
- Case Report; Child; Connecticut; Human; Male;
Skin|PA
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0011-9059
- Country of Publication
- UNITED STATES
Record 6 from
database: MEDLINE
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- Title
- Behavioural and epidemiological considerations
pertaining to necrotic araneism in southern Africa.
- Author
- Newlands G; Atkinson P
- Address
- Department of Community Health, University of
Pretoria.
- Source
- S Afr Med J, 1990 Jan, 77:2, 92-5
- Abstract
- Species of three spider genera are known to
cause dermonecrotic lesions in man. The incidence of necrotic
araneism caused by species of these genera is a function of
their behaviour and their geographical distribution in relation
to areas of high human population density. Evidence based on an
analysis of 39 diagnosed spider bites suggests that sac spiders
(Chiracanthium sp.) are responsible for most spider bites,
followed by violin spiders, Loxosceles sp.
- Language of Publication
- English
- Unique Identifier
- 90117319
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- MeSH Heading (Major)
- Arachnidism|*EP; Spiders|*
- MeSH Heading
- Africa, Southern|EP; Animal; Female; Human;
Male; Necrosis; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0038-2469
- Country of Publication
- SOUTH AFRICA
Record 7 from
database: MEDLINE
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- Title
- Loxoscelism.
- Author
- Futrell JM
- Address
- Tulane University Medical School, Department of
Dermatology, New Orleans, Louisiana 70112.
- Source
- Am J Med Sci, 1992 Oct, 304:4, 261-7
- Abstract
- Loxoscelism, or envenomation by the brown
recluse spider, may result in necrotic lesions and systemic
reactions, including hemolytic anemia. Histologically, it
resembles a cutaneous Arthus reaction. The reaction mechanism
involves interactions between complement, neutrophils, and the
clotting system. It is best treated with analgesics, avoidance
of early surgical debridement, and oral dapsone.
- Language of Publication
- English
- Unique Identifier
- 93035458
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- MeSH Heading (Major)
- Arachnidism|PC/*PP/TH; Spiders|*
- MeSH Heading
- Animal; Human
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0002-9629
- Country of Publication
- UNITED STATES
Record 8 from
database: MEDLINE
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- Title
- Morbidity of Brown Recluse spider bites.
Clinical picture, treatment and prognosis.
- Author
- Ingber A; Trattner A; Cleper R; Sandbank M
- Address
- Department of Dermatology, Beilinson Medical
Center, Petah Tiqva, Israel.
- Source
- Acta Derm Venereol, 1991, 71:4, 337-40
- Abstract
- A retrospective review was made of 35 cases of
Brown Recluse spider bites treated during a period of 21 years.
The most common location of the bite was on the lower limbs,
particularly the thigh. The main systemic manifestations were
fever, malaise and maculopapular rash, but there were no cases
of hemolysis, coagulopathy, or of renal or neurologic
involvement. Signs indicating a poor prognosis appeared to be
lymphangitis, generalized maculopapular rash and location of the
bite on the thigh or abdomen. Most cases were treated
effectively by rest, elevation of the affected part of the body,
local cleansing, and prophylactic antibiotics. On the basis of
this experience it was concluded that only when lesions show a
necrotic area measuring 2 to 3 cm should patients be treated
with systemic corticosteroids. In most such cases,
administration of corticosteroids for 14-21 days proved
sufficient to avoid the need for surgery. Only 5 cases required
surgical intervention.
- Language of Publication
- English
- Unique Identifier
- 92024762
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- MeSH Heading (Major)
- Arachnidism|*EP/PA/TH
- MeSH Heading
- Adolescence; Adult; Aged; Aged, 80 and over;
Child; Comparative Study; Female; Human; Israel|EP; Male; Middle
Age; Morbidity; Necrosis; Prognosis; Retrospective Studies;
Severity of Illness Index
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0001-5555
- Country of Publication
- SWEDEN
Record 9 from
database: MEDLINE
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- Title
- Cutaneous necrosis following a spider bite: a
case report and review.
- Author
- Alario A; Price G; Stahl R; Bancroft P
- Address
-
- Source
- Pediatrics, 1987 Apr, 79:4, 618-21
- Abstract
- Several species of spiders indigenous to the
United States can cause a painful and necrotic wound.
Recognition of the characteristic clinical course is important
to avoid potential complications. A case report and review are
presented.
- Language of Publication
- English
- Unique Identifier
- 87146151
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- MeSH Heading (Major)
- Arachnidism|DI/*PA/SU; Skin|*PA
- MeSH Heading
- Adolescence; Case Report; Diagnosis,
Differential; Female; Human; Knee; Necrosis
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0031-4005
- Country of Publication
- UNITED STATES
Record 10 from
database: MEDLINE
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- Title
- Loxoscelism of the eyelids.
- Author
- Edwards JJ; Anderson RL; Wood JR
- Address
-
- Source
- Arch Ophthalmol, 1980 Nov, 98:11, 1997-2000
- Abstract
- Loxoscelism is a reaction to the bite of
spiders of the genus Loxosceles. Several species have been found
in the United States; the most commonly encountered is L
reclusus, the small brown recluse spider. Two types of reactions
occur from the bite. In the localized type, necrotic loxoscelism,
a cutaneous lesion with extensive gangrene develops. About 25%
of patients have systemic manifestations of viscerocutaneous
loxoscelism. There is the same local reaction, but, in addition,
fever, chills, vomiting, joint pain, and hematologic
abnormalities occur. Hemoglobinemia and hemoglobinuria suggest
severe involvement. Deaths are believed to be caused by massive
intravascular hemolysis. We describe a 61-year-old man who was
bitten on the periorbital region; viscerocutaneous loxoscelism
with gangrenous involvement of the eyelids developed. Severe
laryngeal edema from regional, massive swelling of his neck was
life threatening.
- Language of Publication
- English
- Unique Identifier
- 81061994
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- MeSH Heading (Major)
- Arachnidism|*CO/PA/TH; Eyelid Diseases|*ET/PA/TH
- MeSH Heading
- Case Report; Convulsions|ET; Eyelids|SU;
Gangrene; Human; Male; Middle Age; Respiratory Distress
Syndrome, Adult|ET; Spiders
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0003-9950
- Country of Publication
- UNITED STATES
Record 11 from
database: MEDLINE
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- Title
- Loxoscelism in the Transvaal, South Africa.
- Author
- Newlands G; Isaacson C; Martindale C
- Address
-
- Source
- Trans R Soc Trop Med Hyg, 1982, 76:5, 610-5
- Abstract
- Bites by spiders of the genus Loxosceles have
been implicated as a cause of necrotic arachnidism in the
Transvaal. The identification and natural history of three
species of Loxosceles common in the Transvaal, L. spinulosa, L.
speluncarum and L. parrami, are discussed, the clinical symptoms
of envenomation as observed both in human patients and in
experimental animals are presented, and the histopathological
appearance of the lesion, at different stages of its
development, is described.
- Language of Publication
- English
- Unique Identifier
- 83094374
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- MeSH Heading (Major)
- Arachnidism|*PA/TH
- MeSH Heading
- Animal; Ecology; Human; Male; Rabbits; South
Africa; Spiders|PH; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0035-9203
- Country of Publication
- ENGLAND
Record 12 from
database: MEDLINE
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- Title
- Necrotic arachnidism--Pacific Northwest,
1988-1996.
- Address
-
- Source
- MMWR Morb Mortal Wkly Rep, 1996 May, 45:21,
433-6
- Abstract
- Although spider bites are common in many parts
of the United States, most domestic spiders are not
substantially venomous to man. The best known exceptions are
widow spiders (Latrodectus spp., including the black widow L.
mactans) and brown spiders (Loxesceles spp., particularly the
brown recluse, Lox. reclusa). However, cases of arachnid
envenomation from the hobo spider (Tegenaria agrestis) are being
reported increasingly in the Pacific Northwest. This report
summarizes investigations of three cases of T. agrestis bites
among persons in Idaho, Oregon, and Washington; spider bites
reported to U.S. poison-control centers during 1994; and
emphasizes the need for physicians in the northwestern United
States to consider the species as a cause of toxic arachnidism.
- Language of Publication
- English
- Unique Identifier
- 96218676
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- MeSH Heading (Major)
- Arachnidism|*EP/PP
- MeSH Heading
- Adult; Anemia, Aplastic|ET; Animal; Case
Report; Child; Fatal Outcome; Female; Headache|ET; Hemorrhage|ET;
Human; Leg Ulcer|ET; Male; Middle Age; Necrosis|ET; Northwestern
United States|EP; Skin|PA
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0149-2195
- Country of Publication
- UNITED STATES
Record 13 from
database: MEDLINE
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- Title
- Spider bites.
- Author
- Wong RC; Hughes SE; Voorhees JJ
- Address
-
- Source
- Arch Dermatol, 1987 Jan, 123:1, 98-104
- Abstract
- Spiders are a ubiquitous component of the fauna
of North America. At least 50 to 60 species in the United States
are known to bite humans, although in most cases, the diagnosis
is never suspected nor is treatment necessary. A few species of
spiders are capable of causing necrotic wounds and,
occasionally, death. This review is intended to provide an
overview of the recent advances in the diagnosis and treatment
of spider bites, as well as a compilation of the many species of
spiders that have been reported to give clinically important
bites.
- Language of Publication
- English
- Unique Identifier
- 87098878
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- MeSH Heading (Major)
- Arachnidism|*/TH; Spiders|*
- MeSH Heading
- Animal; Human; Spider Venoms|TO; United States
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0003-987X
- Country of Publication
- UNITED STATES
Record 14 from
database: MEDLINE
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- Title
- Venomous bites and stings in the tropical
world.
- Author
- Warrell DA
- Address
- University of Oxford, Nuffield Department of
Clinical Medicine, John Radcliffe Hospital, Headington, UK.
- Source
- Med J Aust, 1993 Dec, 159:11-12, 773-9
- Abstract
- Snakes of the families Viperidae and Elapidae
are responsible for the high incidence of morbidity and
mortality after snake bites in countries of West Africa, the
Indian subcontinent, South-East Asia, New Guinea and Latin
America. Envenoming can cause local effects, notably tissue
necrosis; and systemic effects, including paralysis, haemostatic
disturbances, shock, increased capillary permeability,
myocardial damage, rhabdomyolysis and acute renal failure.
Specific hyperimmune serum (antivenom) is the mainstay of
medical treatment for severe envenoming. Ancillary treatments
such as assisted ventilation, repletion of circulating volume,
renal dialysis and surgical debridement of necrotic tissues are
needed in some cases. Scorpion stings are a common medical
problem in middle and southern America, North Africa and the
Middle East. Vasodilator drugs are important to counter the
effects of massive catecholamine release. Bites by spiders and
stings by hymenoptera and marine animals are responsible for
deaths and morbidity in some tropical countries.
- Language of Publication
- English
- Unique Identifier
- 94088356
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- MeSH Heading (Major)
- Developing Countries|*; Elapidae|*CL; Snake
Bites|*EP/MO/*PP; Viperidae|*CL
- MeSH Heading
- Animal; Antivenins|TU; Arachnidism|EP/MO; Bees;
Human; Insect Bites and Stings|EP/PP; Scorpions; Spiders;
Tropical Climate
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0025-729X
- Country of Publication
- AUSTRALIA
Record 15 from
database: MEDLINE
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- Title
- Loxosceles reclusa envenomation [see comments]
- Author
- Gendron BP
- Address
- Department of Emergency Medicine, Madigan Army
Medical Center, Tacoma, WA 98431-5382.
- Source
- Am J Emerg Med, 1990 Jan, 8:1, 51-4
- Abstract
- Loxosceles species are widely distributed.
People are most at risk for bites when they disturb the
nocturnal spider's habitat. The bite sequelae range from
insignificant, to disseminated intravascular coagulation and
renal failure. Patients most frequently seek care for
slow-healing necrotic skin lesions. Early surgical excision is
not recommended. Conservative local care usually suffices.
Dapsone may benefit some patients. Specific antivenom given
early may minimize sequelae.
- Language of Publication
- English
- Unique Identifier
- 90088678
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- MeSH Heading (Major)
- Arachnidism|*/TH
- MeSH Heading
- Antivenins|TU; Dapsone|TU; Human; Necrosis|ET/TH;
Spider Venoms
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0735-6757
- Country of Publication
- UNITED STATES
Record 16 from
database: MEDLINE
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- Title
- Brown recluse spider bite. A literature review
and case report.
- Author
- Gutowicz M; Fritz RA; Sonoga AL
- Address
-
- Source
- J Am Podiatr Med Assoc, 1989 Mar, 79:3, 142-6
- Abstract
- A review of the literature on brown recluse
spider bite is presented, including clinical presentation and
treatment. Emphasis is placed on the treatment of local tissue
necrosis. A case report of a severe necrotic ulcer secondary to
a spider bit is presented. Tissue necrosis following a brown
recluse spider bit can be debilitating, and healing may be
prolonged for many months. Even with early treatment, prognosis
often is poor. Future studies might help establish better
treatment regimens.
- Language of Publication
- English
- Unique Identifier
- 89258395
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- MeSH Heading (Major)
- Arachnidism|*CO; Leg Ulcer|*ET
- MeSH Heading
- Case Report; Human; Leg; Male; Middle Age;
Necrosis|ET
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 8750-7315
- Country of Publication
- UNITED STATES
Record 17 from
database: MEDLINE
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- Title
- Management of the brown recluse spider bite.
- Author
- Hollabaugh RS; Fernandes ET
- Address
- Department of Pediatric Surgery, LeBonheur
Children's Hospital, Memphis, TN 38103.
- Source
- J Pediatr Surg, 1989 Jan, 24:1, 126-7
- Abstract
- The objectives in the treatment of the brown
recluse spider bite are to prevent skin necrosis and the need
for reconstructive surgery. A simple technique that consists of
curetting the subcutaneous tissue in the necrotic area of the
lesion, to prevent the local destructive actions of the toxin,
is described. From 1981 to 1987, 18 patients were treated with
this technique. The wounds were generally curetted under local
anesthesia in an outpatient setting. In all but one case, the
erythema, edema, and pain resolved significantly in 24 to 48
hours, and the wounds healed primarily with minimal scarring. We
consider curettage the treatment of choice for brown recluse
spider bites when the lesions are noted in relatively early
stages. It can be performed as an outpatient procedure; it
controls the symptoms and prevents further necrosis, with
excellent cosmetic results.
- Language of Publication
- English
- Unique Identifier
- 89258085
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- MeSH Heading (Major)
- Arachnidism|*SU
- MeSH Heading
- Adolescence; Child; Child, Preschool;
Curettage|MT; Female; Human; Male; Necrosis; Skin|PA/SU
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0022-3468
- Country of Publication
- UNITED STATES
Record 18 from
database: MEDLINE
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- Title
- The management of snake and spider bites in the
southeastern United States.
- Author
- Pennell TC; Babu SS; Meredith JW
- Address
-
- Source
- Am Surg, 1987 Apr, 53:4, 198-204
- Abstract
- Of all snake bites reported in the United
States of America each year, 75 per cent occur in the states
that form the Southeastern Surgical Congress. Pit vipers, coral
snakes, and exotic imported snakes are all found in that area.
Deaths from those snake bites are rare, but morbidity is high
and it is often due to overtreatment rather than undertreatment.
Treatment in the field is rarely necessary for the victim who is
less than 1 hour away from definitive care. The type and size of
the snake and the age, size, and health of the patient are
important guides to therapy. Envenomation may not occur. When
envenomation occurs from pit viper bites, antivenom is not
always necessary, and its inherent dangers (serum sickness and
possible hypersensitivity) must be weighed against the severity
of systemic and local manifestations. All coral snake bites
resulting in envenomation must be treated vigorously with coral
snake antivenom. The Oklahoma City Poison Control Center can
guide the treatment of bites from exotic snakes. The most
frequently encountered toxic spider bites in the Southeast are
those of the black widow and brown recluse spiders. The symptoms
of black widow envenomation are best controlled with calcium
gluconate or a muscle relaxant. Antivenom should be reserved for
severe reactions. Brown recluse necrotic lesions are best
controlled with dapsone.
- Language of Publication
- English
- Unique Identifier
- 87211415
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- MeSH Heading (Major)
- Arachnidism|*TH; Snake Bites|*TH
- MeSH Heading
- Human; United States
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0003-1348
- Country of Publication
- UNITED STATES
Record 19 from
database: MEDLINE
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- Title
- Envenomation by the sac spider Chiracanthium
mildei.
- Author
- Krinsky WL
- Address
-
- Source
- Cutis, 1987 Aug, 40:2, 127-9
- Abstract
- A 19-year-old man was abruptly awakened during
the night by the painful bite of a female sac spider, later
identified as Chiracanthium mildei. An erythematous urticarial
plaque formed immediately. Later, punctate macules appeared, and
the bite site became indurated. The clinical response was
similar to those reported following bites by Chiracanthium
spiders in Japan, Australia, Europe, Massachusetts, Georgia,
Indiana, California, and Hawaii. The necrotic lesions associated
with some of those bites did not occur in this case. This is the
first reported case of C. mildei bite in Connecticut.
- Language of Publication
- English
- Unique Identifier
- 87303150
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- MeSH Heading (Major)
- Arachnidism|*DI; Spiders|*AH
- MeSH Heading
- Adult; Case Report; Connecticut; Human; Male;
Support, U.S. Gov't, P.H.S.
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0011-4162
- Country of Publication
- UNITED STATES
Record 20 from
database: MEDLINE
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- Title
- Successful treatment of disseminated Fusarium
infection in an immunocompromised child.
- Author
- Barrios NJ; Kirkpatrick DV; Murciano A; Stine
K; Van Dyke RB; Humbert JR
- Address
- Department of Pediatrics, Tulane University
Medical School, New Orleans, Louisiana 70112.
- Source
- Am J Pediatr Hematol Oncol, 1990 Fal, 12:3,
319-24
- Abstract
- We report the first know case of disseminated
fungal infection due to Fusarium proliferatum in a bone marrow
transplant recipient to our knowledge. Fusarium was cultured
from the blood, a paranasal sinus, and necrotic skin lesions.
The isolate was sensitive to amphotericin B and on further
sensitivity testing, synergy was demonstrated using rifampin in
combination with amphotericin B. The patient had this infection
while she was receiving alternate-day amphotericin, rifampin,
and 5-flucytosine (5-FC) therapy. The infection was documented
within 48 h of discontinuing daily granulocyte transfusions,
which she had received for 3 weeks. The 5-FC was discontinued
when sensitivities showed the organism resistant. After 6 weeks
of treatment she showed complete remission of the infection,
although neutrophil counts remained below 0.25 X 10(9)/L. From
this case and from a review of the literature, it appears that
synergic antifungal agents combined with leukocyte transfusions
may be beneficial in the successful treatment of fusariosis in
the compromised host.
- Language of Publication
- English
- Unique Identifier
- 91052269
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- MeSH Heading (Major)
- Amphotericin B|AD/*TU; Fusarium|*/IP;
Mycoses|*DT/ET; Opportunistic Infections|*DT/ET; Rifampin|*TU
- MeSH Heading
- Antineoplastic Agents, Combined|TU;
Arachnidism|CO; Aspergillosis|CO; Bone Marrow Transplantation|AE;
Case Report; Child, Preschool; Combined Modality Therapy;
Female; Human; Leukemia, Lymphocytic, Acute|CO/IM/TH;
Neutropenia|CO; Skin|MI; Staphylococcal Infections|CO
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0192-8562
- Country of Publication
- UNITED STATES
Record 21 from
database: MEDLINE
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- Title
- Management of the brown recluse spider bite to
the glans penis.
- Author
- Broughton G 2nd
- Address
- Brooke Army Medical Center, Department of
General Surgery, Fort Sam Houston, TX 78234, USA.
- Source
- Mil Med, 1996 Oct, 161:10, 627-9
- Abstract
- A significant number of people are bitten by
the brown recluse spider (BRS) each year. Medical treatment
regimens are sometimes unsatisfactory and surgical intervention
is often necessary to debride the necrotic wound. This case
study reports the treatment given to a 19-year-old active duty
United States Army soldier who suffered a BRS bite to the glans
penis. This patient received immediate medical attention and was
started on intravenously administered diphenhydramine,
methylprednisolone, calcium gluconate, and famotidine. Oral
dapsone treatment was begun in the emergency room. Within 24
hours after his injury, the patient received his first
hyperbaric oxygen treatment, which was continued twice daily for
5 days. Skin necrosis was avoided, the patient did not require
any surgical intervention, and he was discharged after 8 days
without sequelae.
- Language of Publication
- English
- Unique Identifier
- 97075736
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- MeSH Heading (Major)
- Arachnidism|*DT/*TH; Penis|*
- MeSH Heading
- Adult; Anti-Infective Agents|TU;
Anti-Inflammatory Agents, Steroidal|TU; Calcium Gluconate|TU;
Case Report; Dapsone|TU; Diphenhydramine|TU; Famotidine|TU;
Histamine Antagonists|TU; Human; Hyperbaric Oxygenation; Male;
Methylprednisolone|TU
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0026-4075
- Country of Publication
- UNITED STATES
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